UNC 0646
CAS No. 1320288-17-2
UNC 0646 ( —— )
Catalog No. M22061 CAS No. 1320288-17-2
UNC 0646 is a potent and selective inhibitor of the homologous protein lysine methyltransferases, G9a and GLP (IC50s: 6 nM/15 nM for G9a/GLP).
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
Size | Price / USD | Stock | Quantity |
5MG | 52 | In Stock |
|
10MG | 93 | In Stock |
|
25MG | 173 | In Stock |
|
50MG | 308 | In Stock |
|
100MG | 447 | In Stock |
|
200MG | Get Quote | In Stock |
|
500MG | Get Quote | In Stock |
|
1G | Get Quote | In Stock |
|
Biological Information
-
Product NameUNC 0646
-
NoteResearch use only, not for human use.
-
Brief DescriptionUNC 0646 is a potent and selective inhibitor of the homologous protein lysine methyltransferases, G9a and GLP (IC50s: 6 nM/15 nM for G9a/GLP).
-
DescriptionUNC 0646 is a potent and selective inhibitor of the homologous protein lysine methyltransferases, G9a and GLP (IC50s: 6 nM/15 nM for G9a/GLP). UNC0646 potently blocks G9a/GLP methyltransferase activity in cells (IC50: 10 nM in MCF7 cells); exhibits low cellular toxicity (EC50: 4.7 μM in MCF7 cells).
-
Synonyms——
-
PathwayOthers
-
TargetOther Targets
-
RecptorG9a; GLP
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number1320288-17-2
-
Formula Weight621.9
-
Molecular FormulaC36H59N7O2
-
Purity>98% (HPLC)
-
SolubilityDMSO:30 mg/mL (48.24 mM; Need ultrasonic)
-
SMILESCOC1=C(OCCCN2CCCCC2)C=C2N=C(N=C(NC3CCN(CC3)C3CCCCC3)C2=C1)N1CCCN(CC1)C(C)C
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1.Liu F, et al. Optimization of cellular activity of G9a inhibitors 7-aminoalkoxy-quinazolines. J Med Chem. 2011 Sep 8;54(17):6139-50.
molnova catalog
related products
-
Glucopyranoside,(3be...
Glucopyranoside,(3beta,25R)-17-hydroxyspirost-5-en-3-yl is a natural product for research related to life sciences.
-
DL-2-AMINOOCTANOIC A...
DL-2-Aminooctanoic acid, also known as a-aminocaprylate or alpha-aminocaprylic acid, belongs to the class of organic compounds known as alpha-amino acids.
-
6-Aldehydoisoophiopo...
6-Aldehydoisoophiopogonanone A is a natural product from Ophiopogon japonicus.